Results of Job: search_34f5e8e1-48c4-46b0-83a8-59c3b0fee124

Query Target Key Target Name Description P-Value MaxTC

compound_1

MC5R_MOUSE Mc5r Melanocortin receptor 5 1.611e-191 0.47
NTR2_HUMAN NTSR2 Neurotensin receptor type 2 2.413e-186 0.47
CCKAR_CAVPO CCKAR Cholecystokinin receptor type A 4.62e-164 0.47
HLAA_HUMAN HLA-A HLA class I histocompatibility antigen, A alpha chain 3.051e-159 0.55
CD36_RAT Cd36 Platelet glycoprotein 4 1.301e-154 0.49
NTR1_MOUSE Ntsr1 Neurotensin receptor type 1 3.789e-146 0.52
GRPR_MOUSE Grpr Gastrin-releasing peptide receptor 6.999e-143 0.50
MC4R_MOUSE Mc4r Melanocortin receptor 4 3.289e-140 0.47
NTR1_HUMAN NTSR1 Neurotensin receptor type 1 1.187e-132 0.47
MC3R_MOUSE Mc3r Melanocortin receptor 3 1.066e-129 0.46
MSHR_HUMAN MC1R Melanocyte-stimulating hormone receptor 2.14e-127 0.50
MSHR_MOUSE Mc1r Melanocyte-stimulating hormone receptor 7.458e-127 0.47
EDNRB_RAT Ednrb Endothelin receptor type B 1.515e-115 0.55
GASR_HUMAN CCKBR Gastrin/cholecystokinin type B receptor 2.326e-115 0.48
DSBA_ECOLI dsbA Thiol:disulfide interchange protein DsbA 1.287e-111 0.52
BRCA1_HUMAN BRCA1 Breast cancer type 1 susceptibility protein 1.377e-111 0.41
NTR1_RAT Ntsr1 Neurotensin receptor type 1 6.104e-109 0.41
LSHR_RAT Lhcgr Lutropin-choriogonadotropic hormone receptor 1.207e-108 0.41
OPRM_RAT Oprm1 Mu-type opioid receptor 7.252e-104 0.50
GASR_BOVIN CCKBR Gastrin/cholecystokinin type B receptor 6.66e-101 0.39
MAGI3_HUMAN MAGI3 Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 3 1.942e-98 0.47
RENI_RAT Ren1 Renin 2.77e-97 0.47
MMP11_MOUSE Mmp11 Stromelysin-3 1.468e-93 0.34
EDNRA_MOUSE Ednra Endothelin-1 receptor 1.919e-84 0.54
SORT_HUMAN SORT1 Sortilin 9.852e-83 0.41
MC3R_HUMAN MC3R Melanocortin receptor 3 2.487e-82 0.46
PRO_HTL1A gag-pro Gag-Pro polyprotein 2.655e-82 0.50
NPFF2_RAT Npffr2 Neuropeptide FF receptor 2 6.84e-82 0.41
OPRD_RAT Oprd1 Delta-type opioid receptor 6.43e-79 0.50
OPRD_MOUSE Oprd1 Delta-type opioid receptor 4.097e-77 0.50
KISSR_HUMAN KISS1R KiSS-1 receptor 1.755e-75 0.40
STAT3_HUMAN STAT3 Signal transducer and activator of transcription 3 1.851e-74 0.45
MC4R_HUMAN MC4R Melanocortin receptor 4 6.618e-72 0.50
NK2R_MESAU TACR2 Substance-K receptor 1.231e-71 0.38
OPRM_CAVPO OPRM1 Mu-type opioid receptor 1.93e-71 0.50
GRPR_RAT Grpr Gastrin-releasing peptide receptor 1.061e-70 0.44
Q8CGM4_CAVPO OPRM1 Mu-opioid receptor 7.273e-70 0.36
SURA_ECOLI surA Chaperone SurA 1.978e-69 0.56
PAR2_HUMAN F2RL1 Proteinase-activated receptor 2 8.323e-67 0.34
NK1R_CAVPO TACR1 Substance-P receptor 7.251e-64 0.40
GASR_RAT Cckbr Gastrin/cholecystokinin type B receptor 1.85e-63 0.40
HMDH_MESAU HMGCR 3-hydroxy-3-methylglutaryl-coenzyme A reductase 5.576e-63 0.38
LCAP_HUMAN LNPEP Leucyl-cystinyl aminopeptidase 3.277e-62 0.57
MMP11_HUMAN MMP11 Stromelysin-3 3.196e-61 0.32
EDNRA_PIG EDNRA Endothelin-1 receptor 7.505e-61 0.46
RENI1_MOUSE Ren1 Renin-1 8.533e-61 0.37
ANPRC_HUMAN NPR3 Atrial natriuretic peptide receptor 3 3.975e-58 0.32
SSR2_HUMAN SSTR2 Somatostatin receptor type 2 7.27e-58 0.35
PTPRC_HUMAN PTPRC Receptor-type tyrosine-protein phosphatase C 2.789e-57 0.36
C3AR_HUMAN C3AR1 C3a anaphylatoxin chemotactic receptor 8.984e-49 0.49
ACE_HUMAN ACE Angiotensin-converting enzyme 1.128e-48 0.49
XPP2_RAT Xpnpep2 Xaa-Pro aminopeptidase 2 3.94e-48 0.38
ECE1_HUMAN ECE1 Endothelin-converting enzyme 1 1.63e-46 0.33
NK1R_RAT Tacr1 Substance-P receptor 2.043e-46 0.49
NMUR1_MOUSE Nmur1 Neuromedin-U receptor 1 5.526e-46 0.37
TR10A_HUMAN TNFRSF10A Tumor necrosis factor receptor superfamily member 10A 8.046e-46 0.29
NMUR1_HUMAN NMUR1 Neuromedin-U receptor 1 1.907e-45 0.39
CCKAR_RAT Cckar Cholecystokinin receptor type A 2.715e-45 0.40
FURIN_HUMAN FURIN Furin 3.872e-45 0.35
SSR2_MOUSE Sstr2 Somatostatin receptor type 2 4.773e-45 0.30
NK2R_RAT Tacr2 Substance-K receptor 4.485e-44 0.38
RENI_HUMAN REN Renin 1.855e-43 0.50
NEP_RABIT MME Neprilysin 5.322e-43 0.38
C5AR1_HUMAN C5AR1 C5a anaphylatoxin chemotactic receptor 1 6.328e-42 0.50
NEC1_HUMAN PCSK1 Neuroendocrine convertase 1 8.3e-42 0.34
PCSK5_HUMAN PCSK5 Proprotein convertase subtilisin/kexin type 5 8.3e-42 0.34
CCKAR_MOUSE Cckar Cholecystokinin receptor type A 1.14e-41 0.37
A3EZI9_9HEPC NS3 Genome polyprotein 3.888e-41 0.41
NMBR_RAT Nmbr Neuromedin-B receptor 5.094e-41 0.51
XIAP_HUMAN XIAP E3 ubiquitin-protein ligase XIAP 1.063e-40 0.44
OPRX_MOUSE Oprl1 Nociceptin receptor 3.119e-40 0.31
PEPT1_DERPT DERP1 Peptidase 1 6.748e-40 0.33
FPRS1_MOUSE Fpr-s1 Formyl peptide receptor-related sequence 1 7.964e-40 0.28
CELA1_HUMAN CELA1 Chymotrypsin-like elastase family member 1 1.957e-39 0.36
NMBR_HUMAN NMBR Neuromedin-B receptor 3.373e-39 0.45
EDNRA_HUMAN EDNRA Endothelin-1 receptor 1.247e-37 0.55
CTRA_BOVIN Chymotrypsinogen A 1.393e-37 0.36
Q5D7U5_CHICK OXTR Oxytocin-like receptor 2.055e-37 0.30
TRY1_BOVIN Cationic trypsin 1.086e-36 0.33
BRS3_HUMAN BRS3 Bombesin receptor subtype-3 1.556e-36 0.44
ECE1_BOVIN ECE1 Endothelin-converting enzyme 1 1.838e-36 0.30
ACE_RAT Ace Angiotensin-converting enzyme 5.354e-36 0.38
IL1RA_MOUSE Il1rn Interleukin-1 receptor antagonist protein 1.29e-35 0.28
CBX7_HUMAN CBX7 Chromobox protein homolog 7 6.148e-35 0.35
CATE_HUMAN CTSE Cathepsin E 5.044e-34 0.39
A4HSF7_LEIIN TRYR Trypanothione reductase 1.723e-33 0.42
FSHR_RAT Fshr Follicle-stimulating hormone receptor 2.939e-33 0.41
FKBP5_HUMAN FKBP5 Peptidyl-prolyl cis-trans isomerase FKBP5 3.048e-33 0.38
CDYL2_HUMAN CDYL2 Chromodomain Y-like protein 2 4.247e-32 0.35
THRB_HUMAN F2 Prothrombin 1.382e-31 0.37
NMUR2_HUMAN NMUR2 Neuromedin-U receptor 2 2.102e-31 0.39
XPP2_HUMAN XPNPEP2 Xaa-Pro aminopeptidase 2 2.136e-31 0.38
PGTB1_RAT Pggt1b Geranylgeranyl transferase type-1 subunit beta 1.428e-30 0.38
POLG_CXB3N Genome polyprotein 1.727e-30 0.32
MLX_HUMAN MLX Max-like protein X 1.945e-30 0.32
XPP1_HUMAN XPNPEP1 Xaa-Pro aminopeptidase 1 1.965e-30 0.38
MYLK_CHICK Mylk Myosin light chain kinase, smooth muscle 4.093e-30 0.42
NK3R_CAVPO TACR3 Neuromedin-K receptor 1.871e-29 0.34
AMPN_HUMAN ANPEP Aminopeptidase N 3.462e-29 0.56
PEPA_PIG PGA Pepsin A 1.056e-28 0.40
PAPA1_CARPA Papain 2.282e-28 0.42
CMA1_HUMAN CMA1 Chymase 1.208e-27 0.42
GHSR_HUMAN GHSR Growth hormone secretagogue receptor type 1 2.448e-27 0.49
CCKAR_HUMAN CCKAR Cholecystokinin receptor type A 5.08e-27 0.41
V1BR_HUMAN AVPR1B Vasopressin V1b receptor 9.237e-27 0.33
ECE1_RAT Ece1 Endothelin-converting enzyme 1 1.667e-26 0.36
ACE_RABIT ACE Angiotensin-converting enzyme 1.91e-26 0.43
OPRD_HUMAN OPRD1 Delta-type opioid receptor 2.361e-25 0.50
CASPA_HUMAN CASP10 Caspase-10 2.629e-25 0.44
CP125_MYCTU cyp125 Steroid C26-monooxygenase 4.292e-25 0.31
OPRM_MOUSE Oprm1 Mu-type opioid receptor 1.032e-24 0.48
CATD_BOVIN CTSD Cathepsin D 5.383e-24 0.35
Q72874_9HIV1 pol Pol polyprotein 2.976e-23 0.45
STAT6_HUMAN STAT6 Signal transducer and activator of transcription 6 4.259e-23 0.38
RIR1_MYCTU nrdE Ribonucleoside-diphosphate reductase subunit alpha 5.834e-23 0.37
GNRHR_RAT Gnrhr Gonadotropin-releasing hormone receptor 1.824e-22 0.52
ANPRA_HUMAN NPR1 Atrial natriuretic peptide receptor 1 2.503e-22 0.32
DRB3_HUMAN HLA-DRB3 HLA class II histocompatibility antigen, DR beta 3 chain 3.182e-22 0.29
Q4U254_9ENTO protease Protease 3.281e-22 0.44
ELNE_HUMAN ELANE Neutrophil elastase 3.549e-22 0.41
NEP_RAT Mme Neprilysin 9.73e-22 0.43
CTRC_HUMAN CTRC Chymotrypsin-C 1.19e-21 0.42
OPRK_RAT Oprk1 Kappa-type opioid receptor 2.079e-21 0.50
CFAB_HUMAN CFB Complement factor B 8.139e-21 0.33
D2K2A8_9HEPC NS4A Non-structural protein 4A 9.231e-21 0.41
GASR_MOUSE Cckbr Gastrin/cholecystokinin type B receptor 2.989e-20 0.38
OPRM_HUMAN OPRM1 Mu-type opioid receptor 6.125e-20 0.51
ELAS_PSEAE lasB Elastase 1.56e-19 0.36
MMP8_HUMAN MMP8 Neutrophil collagenase 1.819e-19 0.33
CATB_HUMAN CTSB Cathepsin B 4.868e-19 0.44
TYRO_HUMAN TYR Tyrosinase 8.807e-19 0.37
HMDH_HUMAN HMGCR 3-hydroxy-3-methylglutaryl-coenzyme A reductase 9.756e-19 0.46
OXYR_MOUSE Oxtr Oxytocin receptor 1.054e-18 0.30
NEC2_HUMAN PCSK2 Neuroendocrine convertase 2 1.625e-18 0.29
NRP1_RAT Nrp1 Neuropilin-1 2.356e-18 0.46
OPRK_MOUSE Oprk1 Kappa-type opioid receptor 5.066e-18 0.35
Q9ERC0_RAT Npy2r Neuropeptide Y receptor Y2 5.681e-18 0.28
CP51_TRYCC CYP51 Sterol 14-alpha demethylase 6.08e-18 0.31
PSB8_HUMAN PSMB8 Proteasome subunit beta type-8 1.178e-17 0.36
FNTB_RAT Fntb Protein farnesyltransferase subunit beta 1.668e-17 0.38
GRAB_HUMAN GZMB Granzyme B 1.843e-17 0.34
KEAP1_HUMAN KEAP1 Kelch-like ECH-associated protein 1 1.957e-17 0.38
FNTA_RAT Fnta Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha 2.278e-17 0.38
MMP14_HUMAN MMP14 Matrix metalloproteinase-14 2.295e-17 0.34
CATD_HUMAN CTSD Cathepsin D 2.449e-17 0.39
AMPL_HUMAN LAP3 Cytosol aminopeptidase 2.903e-17 0.38
HGFA_HUMAN HGFAC Hepatocyte growth factor activator 1.11e-16 0.35
V1AR_HUMAN AVPR1A Vasopressin V1a receptor 2.22e-16 0.37
O07911_STAAU agrC AgrC 4.441e-16 0.31
THER_BACTH npr Thermolysin 4.441e-16 0.31
GRPR_HUMAN GRPR Gastrin-releasing peptide receptor 5.551e-16 0.51
SIA4A_HUMAN ST3GAL1 CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1 6.661e-16 0.30
GRB2_HUMAN GRB2 Growth factor receptor-bound protein 2 7.772e-16 0.39
PCSK6_HUMAN PCSK6 Proprotein convertase subtilisin/kexin type 6 7.772e-16 0.34
IDE_HUMAN IDE Insulin-degrading enzyme 1.665e-15 0.33
CASP9_HUMAN CASP9 Caspase-9 1.776e-15 0.44
PSB5_HUMAN PSMB5 Proteasome subunit beta type-5 2.109e-15 0.35
Q9N6S8_PLAFA Cysteine proteinase falcipain 2a 2.22e-15 0.34
NK3R_RAT Tacr3 Neuromedin-K receptor 4.885e-15 0.33
NK1R_HUMAN TACR1 Substance-P receptor 1.177e-14 0.50
BMP1_HUMAN BMP1 Bone morphogenetic protein 1 1.232e-14 0.39
TMPS6_HUMAN TMPRSS6 Transmembrane protease serine 6 1.343e-14 0.31
PEPD_HUMAN PEPD Xaa-Pro dipeptidase 1.998e-14 0.36
PLMN_RAT Plg Plasminogen 3.253e-14 0.30
ACE2_RAT Ace2 Angiotensin-converting enzyme 2 3.408e-14 0.31
B3DH72_DANRE oprd1b Opioid receptor, delta 1b 3.73e-14 0.35
O57585_DANRE oprd1a Opioid receptor homologue 3.73e-14 0.35
CATG_HUMAN CTSG Cathepsin G 7.028e-14 0.36
PCSK7_HUMAN PCSK7 Proprotein convertase subtilisin/kexin type 7 1.785e-13 0.29
OXYR_HUMAN OXTR Oxytocin receptor 1.786e-13 0.33
AGTR2_HUMAN AGTR2 Type-2 angiotensin II receptor 1.974e-13 0.54
OPRK_CAVPO OPRK1 Kappa-type opioid receptor 2.163e-13 0.48
PLK1_HUMAN PLK1 Serine/threonine-protein kinase PLK1 3.773e-13 0.39
NEP_HUMAN MME Neprilysin 3.801e-13 0.34
Q98UH1_DANRE oprm1 Mu opioid receptor-like OR2 7.25e-13 0.35
TM11D_HUMAN TMPRSS11D Transmembrane protease serine 11D 1.102e-12 0.30
CASP4_HUMAN CASP4 Caspase-4 1.155e-12 0.44
RIR1_HUMAN RRM1 Ribonucleoside-diphosphate reductase large subunit 2.044e-12 0.34
NCOR2_HUMAN NCOR2 Nuclear receptor corepressor 2 3.352e-12 0.29
QRFPR_HUMAN QRFPR Pyroglutamylated RF-amide peptide receptor 3.598e-12 0.35
NPFF1_HUMAN NPFFR1 Neuropeptide FF receptor 1 4.462e-12 0.44
PSB9_HUMAN PSMB9 Proteasome subunit beta type-9 4.513e-12 0.36
V2R_PIG AVPR2 Vasopressin V2 receptor 5.603e-12 0.30
NPFF2_HUMAN NPFFR2 Neuropeptide FF receptor 2 7.026e-12 0.44
TPP2_RAT Tpp2 Tripeptidyl-peptidase 2 1.259e-11 0.36
TRFR_MOUSE Trhr Thyrotropin-releasing hormone receptor 1.325e-11 0.31
P2Y12_HUMAN P2RY12 P2Y purinoceptor 12 2.146e-11 0.31
Q6MGC4_RAT Pfdn6 H2-K region expressed gene 2, rat orthologue 3.009e-11 0.33
MMP9_HUMAN MMP9 Matrix metalloproteinase-9 3.739e-11 0.33
TETX_CLOTE tetX Tetanus toxin 3.771e-11 0.30
AMD_HUMAN PAM Peptidyl-glycine alpha-amidating monooxygenase 3.83e-11 0.35
NK2R_RABIT TACR2 Substance-K receptor 3.918e-11 0.38
CASP1_HUMAN CASP1 Caspase-1 4.213e-11 0.44
EDNRB_PIG EDNRB Endothelin receptor type B 4.456e-11 0.35
Q95PM0_TRYBR rhodesain Cysteine protease 5.379e-11 0.37
NK2R_HUMAN TACR2 Substance-K receptor 5.811e-11 0.52
V2R_HUMAN AVPR2 Vasopressin V2 receptor 1.072e-10 0.33
BIRC3_HUMAN BIRC3 Baculoviral IAP repeat-containing protein 3 1.428e-10 0.41
Q82134_9DELA prt Protease 2.124e-10 0.50
HEPS_HUMAN HPN Serine protease hepsin 2.797e-10 0.35
CBX4_HUMAN CBX4 E3 SUMO-protein ligase CBX4 3.241e-10 0.35
PLK2_HUMAN PLK2 Serine/threonine-protein kinase PLK2 3.585e-10 0.35
PPCE_BOVIN PREP Prolyl endopeptidase 4.574e-10 0.32
Q82323_9DELA Protease 5.434e-10 0.50
CBX8_HUMAN CBX8 Chromobox protein homolog 8 5.832e-10 0.29
CTRB1_HUMAN CTRB1 Chymotrypsinogen B 7.201e-10 0.36
TAT_HV1H2 tat Protein Tat 7.541e-10 0.29
PRTN3_HUMAN PRTN3 Myeloblastin 7.801e-10 0.29
MMP1_HUMAN MMP1 Interstitial collagenase 1.026e-09 0.34
Q8I6Z5_PLAF7 Plasmepsin V 1.141e-09 0.30
GHRHR_RAT Ghrhr Growth hormone-releasing hormone receptor 1.246e-09 0.28
PSB2_HUMAN PSMB2 Proteasome subunit beta type-2 1.454e-09 0.35
MC5R_HUMAN MC5R Melanocortin receptor 5 1.497e-09 0.46
PEPC_HUMAN PGC Gastricsin 1.532e-09 0.29
NTR2_RAT Ntsr2 Neurotensin receptor type 2 1.692e-09 0.41
ST14_HUMAN ST14 Suppressor of tumorigenicity 14 protein 1.775e-09 0.35
MMP8_RAT Mmp8 Neutrophil collagenase 4.226e-09 0.28
EDNRA_RAT Ednra Endothelin-1 receptor 4.754e-09 0.37
UBC9_HUMAN UBE2I SUMO-conjugating enzyme UBC9 4.912e-09 0.37
S15A2_RAT Slc15a2 Solute carrier family 15 member 2 5.076e-09 0.30
CTRL_HUMAN CTRL Chymotrypsin-like protease CTRL-1 5.367e-09 0.30
CCNA2_HUMAN CCNA2 Cyclin-A2 6.065e-09 0.37
CBPA1_BOVIN CPA1 Carboxypeptidase A1 6.728e-09 0.33
V1BR_RAT Avpr1b Vasopressin V1b receptor 7.722e-09 0.30
MMP2_HUMAN MMP2 72 kDa type IV collagenase 8.008e-09 0.33
CATL1_HUMAN CTSL Cathepsin L1 9.178e-09 0.35
ERAP2_HUMAN ERAP2 Endoplasmic reticulum aminopeptidase 2 9.717e-09 0.32
SSR1_HUMAN SSTR1 Somatostatin receptor type 1 9.865e-09 0.30
CASP5_HUMAN CASP5 Caspase-5 1.315e-08 0.44
LEP_ECOLI lepB Signal peptidase I 1.423e-08 0.34
PPIA_HUMAN PPIA Peptidyl-prolyl cis-trans isomerase A 1.799e-08 0.47
ADCY5_HUMAN ADCY5 Adenylate cyclase type 5 3.801e-08 0.35
Q9ERT1_MOUSE TRH-R2 Thyrotropin-releasing hormone receptor 2 4.553e-08 0.28
O90781_9PLVG HIV-1 protease HIV-1 protease 6.026e-08 0.32
V1AR_RAT Avpr1a Vasopressin V1a receptor 6.297e-08 0.32
MEN1_HUMAN MEN1 Menin 8.257e-08 0.51
TAAR1_HUMAN TAAR1 Trace amine-associated receptor 1 1.123e-07 0.33
CASP2_HUMAN CASP2 Caspase-2 1.376e-07 0.29
PIN1_HUMAN PIN1 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 1.382e-07 0.39
ACE_MOUSE Ace Angiotensin-converting enzyme 1.41e-07 0.31
BACE1_HUMAN BACE1 Beta-secretase 1 1.427e-07 0.39
Q9YQ12_9HIV1 protease Protease 1.872e-07 0.44
NK3R_HUMAN TACR3 Neuromedin-K receptor 2.272e-07 0.39
MRP2_RAT Abcc2 Canalicular multispecific organic anion transporter 1 2.72e-07 0.33
ERAP1_HUMAN ERAP1 Endoplasmic reticulum aminopeptidase 1 3.687e-07 0.32
CCND1_HUMAN CCND1 G1/S-specific cyclin-D1 5.223e-07 0.33
OPRX_HUMAN OPRL1 Nociceptin receptor 5.309e-07 0.33
CYSK_MYCTU cysK1 O-acetylserine sulfhydrylase 1.015e-06 0.30
SSR3_HUMAN SSTR3 Somatostatin receptor type 3 1.437e-06 0.31
BXA1_CLOBH botA Botulinum neurotoxin type A 2.048e-06 0.28
ACE2_HUMAN ACE2 Angiotensin-converting enzyme 2 2.638e-06 0.33
ITB1_HUMAN ITGB1 Integrin beta-1 3.797e-06 0.36
DRD1_HUMAN DRD1 D(1A) dopamine receptor 4.057e-06 0.41
SSR4_HUMAN SSTR4 Somatostatin receptor type 4 5.271e-06 0.30
Q91H74_9FLAV Genome polyprotein 6.017e-06 0.32
STAT3_MOUSE Stat3 Signal transducer and activator of transcription 3 6.924e-06 0.44
ITA4_HUMAN ITGA4 Integrin alpha-4 6.963e-06 0.36
PLMN_HUMAN PLG Plasminogen 7.512e-06 0.33
FPR1_HUMAN FPR1 fMet-Leu-Phe receptor 7.676e-06 0.38
UR2R_RAT Uts2r Urotensin-2 receptor 7.907e-06 0.35