Results of Job: search_0f8bba90-c973-428b-825b-e55021cab7e5

Query Target Key Target Name Description P-Value MaxTC

compound_5

DHC24_HUMAN DHCR24 Delta(24)-sterol reductase 1.487e-84 0.72
CP17A_HUMAN CYP17A1 Steroid 17-alpha-hydroxylase/17,20 lyase 7.421e-82 0.67
NPCL1_HUMAN NPC1L1 NPC1-like intracellular cholesterol transporter 1 1.147e-71 0.69
SIA4B_RAT St3gal2 CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 2 1.585e-66 0.35
CP11A_BOVIN CYP11A1 Cholesterol side-chain cleavage enzyme, mitochondrial 2.011e-65 0.52
EPHA2_MOUSE Epha2 Ephrin type-A receptor 2 4.232e-65 0.39
CP17A_RAT Cyp17a1 Steroid 17-alpha-hydroxylase/17,20 lyase 8.214e-65 0.55
Q9GRG7_9TRYP g6pd Glucose-6-phosphate 1-dehydrogenase 6.005e-64 0.50
CP125_MYCTU cyp125 Steroid C26-monooxygenase 1.597e-56 0.71
CRYAB_HUMAN CRYAB Alpha-crystallin B chain 2.94e-55 0.69
DHCR7_RAT Dhcr7 7-dehydrocholesterol reductase 9.436e-55 0.72
VDR_RAT Vdr Vitamin D3 receptor 1.105e-50 0.32
VDR_BOVIN VDR Vitamin D3 receptor 4.439e-47 0.30
GPBAR_HUMAN GPBAR1 G-protein coupled bile acid receptor 1 5.112e-45 0.50
S5A2_HUMAN SRD5A2 3-oxo-5-alpha-steroid 4-dehydrogenase 2 5.647e-44 0.55
3BHS_MYCTU 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase 8.101e-42 0.37
NTCP_HUMAN SLC10A1 Sodium/bile acid cotransporter 1.245e-41 0.38
MRP4_HUMAN ABCC4 Multidrug resistance-associated protein 4 5.05e-40 0.35
VDR_PIG VDR Vitamin D3 receptor 1.317e-37 0.30
VTDB_HUMAN GC Vitamin D-binding protein 1.317e-37 0.30
VDRA_DANRE vdra Vitamin D3 receptor A 1.159e-36 0.30
SMT1_ARATH SMT1 Cycloartenol-C-24-methyltransferase 1.338e-36 0.59
CDC45_HUMAN CDC45 Cell division control protein 45 homolog 2.333e-36 0.29
CP17A_MACFA CYP17A1 Steroid 17-alpha-hydroxylase/17,20 lyase 4.232e-36 0.45
SHBG_HUMAN SHBG Sex hormone-binding globulin 6.425e-36 0.53
CBG_HUMAN SERPINA6 Corticosteroid-binding globulin 1.733e-34 0.53
S5A1_HUMAN SRD5A1 3-oxo-5-alpha-steroid 4-dehydrogenase 1 9.751e-31 0.45
VDR_HUMAN VDR Vitamin D3 receptor 3.826e-29 0.40
CAH4_BOVIN CA4 Carbonic anhydrase 4 2.096e-28 0.37
NTCP2_HUMAN SLC10A2 Ileal sodium/bile acid cotransporter 2.19e-28 0.38
NPC1_HUMAN NPC1 NPC intracellular cholesterol transporter 1 9.23e-26 0.50
FGF2_HUMAN FGF2 Fibroblast growth factor 2 1.082e-25 0.57
CD4_HUMAN CD4 T-cell surface glycoprotein CD4 1.246e-25 0.32
NR1H3_HUMAN NR1H3 Oxysterols receptor LXR-alpha 3.721e-25 0.78
MPIP1_HUMAN CDC25A M-phase inducer phosphatase 1 2.865e-24 0.35
VDR_CHICK VDR Vitamin D3 receptor 5.389e-23 0.30
G6PD_HUMAN G6PD Glucose-6-phosphate 1-dehydrogenase 8.333e-21 0.53
ERG2_YEAST ERG2 C-8 sterol isomerase 8.417e-21 0.40
NR1H4_HUMAN NR1H4 Bile acid receptor 5.297e-19 0.40
SIA4A_HUMAN ST3GAL1 CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1 2.14e-18 0.35
S22A3_RAT Slc22a3 Solute carrier family 22 member 3 2.898e-18 0.29
ESR2_HUMAN ESR2 Estrogen receptor beta 2.22e-16 0.49
ECR_DROME EcR Ecdysone receptor 3.331e-16 0.30
DPOLA_HUMAN POLA1 DNA polymerase alpha catalytic subunit 6.661e-16 0.53
ANDR_HUMAN AR Androgen receptor 9.992e-16 0.49
CP24A_HUMAN CYP24A1 1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial 9.992e-16 0.30
EBP_HUMAN EBP 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase 4.663e-15 0.46
RORA_HUMAN RORA Nuclear receptor ROR-alpha 7.661e-15 0.50
SRBP2_HUMAN SREBF2 Sterol regulatory element-binding protein 2 3.608e-14 0.69
REST_BORBU resT Telomere resolvase ResT 4.308e-14 0.35
ABCBB_HUMAN ABCB11 Bile salt export pump 4.73e-14 0.35
S22A2_RAT Slc22a2 Solute carrier family 22 member 2 5.473e-14 0.29
EPHA7_HUMAN EPHA7 Ephrin type-A receptor 7 1.131e-12 0.52
EPHA5_HUMAN EPHA5 Ephrin type-A receptor 5 2.131e-12 0.52
ANDR_RAT Ar Androgen receptor 4.631e-12 0.35
ESR1_HUMAN ESR1 Estrogen receptor 4.85e-12 0.49
EPHA8_HUMAN EPHA8 Ephrin type-A receptor 8 6.832e-12 0.52
EPHB3_HUMAN EPHB3 Ephrin type-B receptor 3 6.832e-12 0.52
EPHA4_HUMAN EPHA4 Ephrin type-A receptor 4 1.949e-11 0.52
CP19A_HUMAN CYP19A1 Aromatase 5.349e-11 0.52
EPHA1_HUMAN EPHA1 Ephrin type-A receptor 1 7.829e-11 0.52
EPHB1_HUMAN EPHB1 Ephrin type-B receptor 1 7.829e-11 0.52
EPHA6_HUMAN EPHA6 Ephrin type-A receptor 6 1.194e-10 0.52
EPHB2_HUMAN EPHB2 Ephrin type-B receptor 2 1.788e-10 0.52
CAH2_HUMAN CA2 Carbonic anhydrase 2 2.379e-10 0.37
SHH_MOUSE Shh Sonic hedgehog protein 2.576e-10 0.59
CAH1_HUMAN CA1 Carbonic anhydrase 1 7.118e-10 0.37
EPHA2_HUMAN EPHA2 Ephrin type-A receptor 2 7.294e-10 0.56
S5A1_RAT Srd5a1 3-oxo-5-alpha-steroid 4-dehydrogenase 1 1.042e-09 0.33
EPHB6_HUMAN EPHB6 Ephrin type-B receptor 6 1.066e-09 0.52
CP27B_HUMAN CYP27B1 25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial 1.712e-09 0.30
ENPP2_HUMAN ENPP2 Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 2.558e-09 0.33
FABPL_RAT Fabp1 Fatty acid-binding protein, liver 4.099e-09 0.28
EPHA3_HUMAN EPHA3 Ephrin type-A receptor 3 1.006e-08 0.52
GLI1_HUMAN GLI1 Zinc finger protein GLI1 1.206e-08 0.31
DPOLB_RAT Polb DNA polymerase beta 3.392e-08 0.40
Q9N1N9_HORSE BCHE Carboxylic ester hydrolase 4.512e-08 0.58
DHB3_RAT Hsd17b3 Testosterone 17-beta-dehydrogenase 3 8.775e-08 0.30
SO1A1_RAT Slco1a1 Solute carrier organic anion transporter family member 1A1 1.155e-07 0.31
ANDR_MOUSE Ar Androgen receptor 1.402e-07 0.31
NR1H2_HUMAN NR1H2 Oxysterols receptor LXR-beta 1.74e-07 0.69
Q690N0_BOVIN PGR Progesterone receptor 2.168e-07 0.31
SHH_HUMAN SHH Sonic hedgehog protein 6.604e-07 0.31
HRH3_RAT Hrh3 Histamine H3 receptor 6.832e-07 0.35
RORG_HUMAN RORC Nuclear receptor ROR-gamma 9.479e-07 0.78
S22A3_HUMAN SLC22A3 Solute carrier family 22 member 3 3.105e-06 0.28
GBA2_HUMAN GBA2 Non-lysosomal glucosylceramidase 9.167e-06 0.48

compound_4

DPOLB_RAT Polb DNA polymerase beta 4.749e-67 0.73
CD81_HUMAN CD81 CD81 antigen 1.447e-64 0.52
PYGM_RABIT PYGM Glycogen phosphorylase, muscle form 6.459e-64 0.73
PTN2_HUMAN PTPN2 Tyrosine-protein phosphatase non-receptor type 2 1.437e-61 0.73
PA2A1_ECHCA Acidic phospholipase A2 EC-I 2.763e-58 0.73
PA2B1_NAJME Basic phospholipase A2 1 2.763e-58 0.73
PA2BA_PROFL Basic phospholipase A2 PLA-A 2.763e-58 0.73
DHI2_RAT Hsd11b2 Corticosteroid 11-beta-dehydrogenase isozyme 2 1.668e-53 0.43
PTN1_HUMAN PTPN1 Tyrosine-protein phosphatase non-receptor type 1 5.537e-46 0.76
DHI2_HUMAN HSD11B2 Corticosteroid 11-beta-dehydrogenase isozyme 2 3.115e-32 0.46
CP51A_RAT Cyp51a1 Lanosterol 14-alpha demethylase 1.481e-21 0.36
AK1BA_HUMAN AKR1B10 Aldo-keto reductase family 1 member B10 3.297e-20 0.73
IL1B_HUMAN IL1B Interleukin-1 beta 1.11e-16 0.32
PTN6_HUMAN PTPN6 Tyrosine-protein phosphatase non-receptor type 6 2.22e-16 0.51
EST2_HUMAN CES2 Cocaine esterase 6.661e-16 0.61
TF_HUMAN F3 Tissue factor 6.439e-15 0.57
B7UUK1_APIME pla2 Phospholipase A2 6.173e-14 0.30
CAH2_BOVIN CA2 Carbonic anhydrase 2 1.342e-13 0.51
DHI2_MOUSE Hsd11b2 Corticosteroid 11-beta-dehydrogenase isozyme 2 1.965e-13 0.29
TPH1_RAT Tph1 Tryptophan 5-hydroxylase 1 3.446e-12 0.36
Q9YQ12_9HIV1 protease Protease 4.32e-12 0.73
PLCG1_HUMAN PLCG1 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 7.55e-12 0.48
PIN1_HUMAN PIN1 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 3.661e-11 0.40
PPAC_HUMAN ACP1 Low molecular weight phosphotyrosine protein phosphatase 7.721e-10 0.73
DPOLB_HUMAN POLB DNA polymerase beta 3.113e-09 0.57
UBP7_HUMAN USP7 Ubiquitin carboxyl-terminal hydrolase 7 9.231e-09 0.73
DHI1_MOUSE Hsd11b1 Corticosteroid 11-beta-dehydrogenase isozyme 1 2.032e-08 0.43
TF65_HUMAN RELA Transcription factor p65 3.93e-08 0.73
PTPRF_HUMAN PTPRF Receptor-type tyrosine-protein phosphatase F 1.233e-07 0.73
DHI1_HUMAN HSD11B1 Corticosteroid 11-beta-dehydrogenase isozyme 1 1.268e-07 0.73
GPBAR_HUMAN GPBAR1 G-protein coupled bile acid receptor 1 1.724e-06 0.73
LSS_RAT Lss Lanosterol synthase 1.793e-06 0.32

compound_6

RBBP7_HUMAN RBBP7 Histone-binding protein RBBP7 7.101e-36 0.28
SUZ12_HUMAN SUZ12 Polycomb protein SUZ12 4.634e-26 0.29
Q4QYD9_RAT Heat sensitive channel TRPV3 3.761e-24 0.29
RBBP4_HUMAN RBBP4 Histone-binding protein RBBP4 5.662e-15 0.28
UB2D3_HUMAN UBE2D3 Ubiquitin-conjugating enzyme E2 D3 5.641e-13 0.28
ACHB_TETCF CHRNB1 Acetylcholine receptor subunit beta 1.181e-08 0.29
ACHG_TETCF CHRNG Acetylcholine receptor subunit gamma 1.181e-08 0.29
ACHD_TETCF chrnd Acetylcholine receptor subunit delta 9.328e-08 0.29
MYB_CHICK MYB Transcriptional activator Myb 1.241e-06 0.30

compound_2

KPCA_BOVIN PRKCA Protein kinase C alpha type 5.342e-20 0.34

compound_3

KPCA_BOVIN PRKCA Protein kinase C alpha type 5.342e-20 0.34

compound_1

KPCA_BOVIN PRKCA Protein kinase C alpha type 1.879e-19 0.34